Recombinant human ERLIN2 protein
ERLIN2, also known as SPFH2, is SPFH domain-containing proteins that belong to the prohibitin family. Also, this protein is a ubiquitously expressed 339 amino acid protein that belongs to the band 7/mec-2 family. Localized to lipid raft-like domains in the membrane of the endoplasmic reticulum (ER), ERLIN2 plays a crucial role in the ER-associated degradation (ERAD) pathway that removes metabolically regulated and aberrant proteins from the ER. Recombinant human ERLIN2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Erlin-2, C8orf2, Erlin-2, NET32, SPFH2, SPG18
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
37.8 kDa (338aa)
Additionnal Information
References & Citations
Browman D T., et al. (2006) J Cell Sci. 119:3149-60.; ; Ikeqawa S., et al. (1999) Cytogenet Cell Genet. 85:227-231.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_009106
Uniprot Accession Number
O94905
Species
Human
AA Sequence
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