Recombinant human ERLIN2 protein

ERLIN2, also known as SPFH2, is SPFH domain-containing proteins that belong to the prohibitin family. Also, this protein is a ubiquitously expressed 339 amino acid protein that belongs to the band 7/mec-2 family. Localized to lipid raft-like domains in the membrane of the endoplasmic reticulum (ER), ERLIN2 plays a crucial role in the ER-associated degradation (ERAD) pathway that removes metabolically regulated and aberrant proteins from the ER. Recombinant human ERLIN2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Erlin-2, C8orf2, Erlin-2, NET32, SPFH2, SPG18

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

37.8 kDa (338aa)

Additionnal Information

ERLIN2, Erlin-2, C8orf2, Erlin-2, NET32, SPFH2, SPG18, ATGP1782-10 µg, ATGP1782-20 µg, ATGP1782-50 µg, ATGP1782-100 µg, ATGP1782-250 µg, ATGP1782-500 µg, ATGP1782-1 mg, ATGP1782-10, ATGP1782-20, ATGP1782-50, ATGP1782-100, ATGP1782-250, ATGP1782-500, ATGP1782-1

References & Citations

Browman D T., et al. (2006) J Cell Sci. 119:3149-60.; ; Ikeqawa S., et al. (1999) Cytogenet Cell Genet. 85:227-231.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_009106

Uniprot Accession Number

O94905

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSKIEEGHI GVYYRGGALL TSTSGPGFHL MLPFITSYKS VQTTLQTDEV KNVPCGTSGG VMIYFDRIEV VNFLVPNAVY DIVKNYTADY DKALIFNKIH HELNQFCSVH TLQEVYIELF DQIDENLKLA LQQDLTSMAP GLVIQAVRVT KPNIPEAIRR NYELMESEKT KLLIAAQKQK VVEKEAETER KKALIEAEKV AQVAEITYGQ KVMEKETEKK ISEIEDAAFL AREKAKADAE CYTAMKIAEA NKLKLTPEYL QLMKYKAIAS NSKIYFGKDI PNMFMDSAGS VSKQFEGLAD KLSFGLEDEP LETATKEN