Recombinant human SPSB2 protein

SPSB2 is a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. This protein is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Recombinant human SPSB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

SPRY domain-containing SOCS box protein 2, GRCC9, SSB2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

31.2 kDa (287aa) confirmed by MALDI-TOF

Additionnal Information

SPSB2, SPRY domain-containing SOCS box protein 2, GRCC9, SSB2, ATGP1780-10 µg, ATGP1780-20 µg, ATGP1780-50 µg, ATGP1780-100 µg, ATGP1780-250 µg, ATGP1780-500 µg, ATGP1780-1 mg, ATGP1780-10, ATGP1780-20, ATGP1780-50, ATGP1780-100, ATGP1780-250, ATGP1780-500, ATGP1780-1

References & Citations

Wang, D., et al. (2005) Sect J. Biol. Chem. 280 (16), 16393-16401

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol,1mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_001139788

Uniprot Accession Number

Q99619

Species

Human

AA Sequence

MGQTAL AGGSSSTPTP QALYPDLSCP EGLEELLSAP PPDLGAQRRH GWNPKDCSEN IEVKEGGLYF ERRPVAQSTD GARGKRGYSR GLHAWEISWP LEQRGTHAVV GVATALAPLQ TDHYAALLGS NSESWGWDIG RGKLYHQSKG PGAPQYPAGT QGEQLEVPER LLVVLDMEEG TLGYAIGGTY LGPAFRGLKG RTLYPAVSAV WGQCQVRIRY LGERRAEPHS LLHLSRLCVR HNLGDTRLGQ VSALPLPPAM KRYLLYQ