Recombinant human PDZD11 protein

PDZD11, also known as AIPP1a, is a cytosolic protein which contains one PDZ (DHR) domain. This protein bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. It is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. Recombinant human PDZD11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

PDZ domain-containing protein 11, AIPP1; PDZK11; PISP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

18.5 kDa (163aa) confirmed by MALDI-TOF

Additionnal Information

PDZD11, PDZ domain-containing protein 11, AIPP1; PDZK11; PISP, ATGP1779-10 µg, ATGP1779-20 µg, ATGP1779-50 µg, ATGP1779-100 µg, ATGP1779-250 µg, ATGP1779-500 µg, ATGP1779-1 mg, ATGP1779-10, ATGP1779-20, ATGP1779-50, ATGP1779-100, ATGP1779-250, ATGP1779-500, ATGP1779-1

References & Citations

Stephenson SE., et al. (1996) . J Biol Chem. 280 (39) :33270-9. ; ; Goellner GM, et al. (2003) . Ann N Y Acad Sci. 986:461-71.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Other

NCBI Accession Number

NP_057568

Uniprot Accession Number

Q5EBL8

Species

Human

AA Sequence

MGSMDSRIPY DDYPVVFLPA YENPPAWIPP HERVHHPDYN NELTQFLPRT ITLKKPPGAQ LGFNIRGGKA SQLGIFISKV IPDSDAHRAG LQEGDQVLAV NDVDFQDIEH SKAVEILKTA REISMRVRFF PYNYHRQKER TVH