Recombinant human PDZD11 protein
PDZD11, also known as AIPP1a, is a cytosolic protein which contains one PDZ (DHR) domain. This protein bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. It is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. Recombinant human PDZD11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
PDZ domain-containing protein 11, AIPP1; PDZK11; PISP
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
18.5 kDa (163aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Stephenson SE., et al. (1996) . J Biol Chem. 280 (39) :33270-9. ; ; Goellner GM, et al. (2003) . Ann N Y Acad Sci. 986:461-71.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Scientific Category
Other
NCBI Accession Number
NP_057568
Uniprot Accession Number
Q5EBL8
Species
Human
AA Sequence
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