Recombinant human TREM1 protein

TREM1 is a receptor belonging to the Ig super family that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. Recombinant human TREM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Triggering receptor expressed on myeloid cells 1, CD354, TREM-1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

23.3 kDa (209aa) confirmed by MALDI-TOF

Additionnal Information

TREM1, Triggering receptor expressed on myeloid cells 1, CD354, TREM-1, ATGP1771-10 µg, ATGP1771-20 µg, ATGP1771-50 µg, ATGP1771-100 µg, ATGP1771-250 µg, ATGP1771-500 µg, ATGP1771-1 mg, ATGP1771-10, ATGP1771-20, ATGP1771-50, ATGP1771-100, ATGP1771-250, ATGP1771-500, ATGP1771-1

References & Citations

Kwofie, L., et al. (2012) Sect Ann. Hematol. 91 (4), 605-611; ; Wang, J., et al. (2012) Mol Med Report 5 (3), 663-667

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol,1mM DTT

Scientific Category

Immunology

NCBI Accession Number

NP_061113.1

Uniprot Accession Number

Q9NP99

Species

Human

AA Sequence

ATKLTE EKYELKEGQT LDVKCDYTLE KFASSQKAWQ IIRDGEMPKT LACTERPSKN SHPVQVGRII LEDYHDHGLL RVRMVNLQVE DSGLYQCVIY QPPKEPHMLF DRIRLVVTKG FSGTPGSNEN STQNVYKIPP TTTKALCPLY TSPRTVTQAP PKSTADVSTP DSEINLTNVT DIIRVPVFN