Recombinant human XAGE1A protein
G antigen family D member 2, also known as XAGE1A, is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Recombinant human XAGE1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
G antigen family D member 2, CT12.1, CT12.1A, CTP9, GAGED2, XAGE1, XAGE1B, XAGE1C, XAGE1D, XAGE1E
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
11.5 kDa (104aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Egland K.A., et al. (2002) Mol. Cancer Ther. 1:441-450; ; Sato S., et al. (2007) Cancer Immun. 7:5-5
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 2mM DTT, 30% glycerol, 0.1mM PMSF
Scientific Category
Cancer
NCBI Accession Number
NP_001091061.2
Uniprot Accession Number
Q9HD64
Species
Human
AA Sequence
MESPKKK NQQLKVGILH LGSRQKKIRI QLRSQCATWK VICKSCISQT PGINLDLGSG VKVKIIPKEE HCKMPEAGEE QPQV
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
