Recombinant mouse Galectin-7/LGALS7 protein
Lglas7, also known as galectin7, is a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. It is expressed mainly in stratified squamous epithelium. Lgals7 protein is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. Recombinant mouse Lgals7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Specifications
Product Name Alternative
Lgals7, Galectin-7, Pig1
Expression System
E.coli
Antigen Species
Mouse
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
17.6 kDa (159aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Magnaldo T., et al. (1995) Dev Biol. 168 (2) :259-71. ; ; Magnaldo T., et al. (1998) Differentiation. 63 (3) :159-68.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 2mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_032522
Uniprot Accession Number
Q9CRB1
Species
Mouse
AA Sequence
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