Recombinant mouse Galectin-7/LGALS7 protein

Lglas7, also known as galectin7, is a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. It is expressed mainly in stratified squamous epithelium. Lgals7 protein is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. Recombinant mouse Lgals7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Product Specifications

Product Name Alternative

Lgals7, Galectin-7, Pig1

Expression System

E.coli

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

17.6 kDa (159aa) confirmed by MALDI-TOF

Additionnal Information

Pig-1, Pig1, Pig 1, Lgals-7, Lgals7, Lgals 7, Galectin-7, Galectin7, Galectin 7, ATGP1759-10 µg, ATGP1759-20 µg, ATGP1759-50 µg, ATGP1759-100 µg, ATGP1759-250 µg, ATGP1759-500 µg, ATGP1759-1 mg, ATGP1759-010, ATGP1759-020, ATGP1759-050, ATGP1759-100, ATGP1759-250, ATGP1759-500, ATGP1759-01M

References & Citations

Magnaldo T., et al. (1995) Dev Biol. 168 (2) :259-71. ; ; Magnaldo T., et al. (1998) Differentiation. 63 (3) :159-68.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 2mM DTT

Scientific Category

Cancer

NCBI Accession Number

NP_032522

Uniprot Accession Number

Q9CRB1

Species

Mouse

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSATQHK TSLPQGVRVG TVMRIRGMVP DQAGRFHVNL LCGEEQGADA ALHFNPRLDT SEVVFNTKEQ GKWGREERGT GIPFERGQPF EVLLIATEEG FKAVVGDDEY LHFHHRMPPA RVRLVEVGGD VQLHSVKIF