Recombinant human MRTO4 protein

MRNA turnover protein 4 homolog, also known as MRTO4, belongs to the ribosomal protein L10P family. MRTO4 is a nucleolar component of the ribosome assembly machinery that shares notable similarity and competes for binding to the 25S rRNA GAR domain with the ribosomal protein P0. The gene encoding MRTO4 maps to human chromosome 1, which spans 260 million base pairs, contains over 3, 000 genes and comprises nearly 8% of the human genome. Recombinant human MRTO4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

MRNA turnover protein 4 homolog, C1orf33, dJ657E11.4, MRT4

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

29.9 kDa (262aa) confirmed by MALDI-TOF

Additionnal Information

MRTO4, mRNA turnover protein 4 homolog, C1orf33, dJ657E11.4, MRT4, ATGP1741-10 µg, ATGP1741-20 µg, ATGP1741-50 µg, ATGP1741-100 µg, ATGP1741-250 µg, ATGP1741-500 µg, ATGP1741-1 mg, ATGP1741-10, ATGP1741-20, ATGP1741-50, ATGP1741-100, ATGP1741-250, ATGP1741-500, ATGP1741-1

References & Citations

Michalec B., et al. (2010) Int J Biochem Cell Biol. 42 (5) :736-48; ; Weise A., et al. (2005) Cytoqenet Genome Res. 108: 217-222.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol,1mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_057267

Uniprot Accession Number

Q9UKD2

Species

Human

AA Sequence

MPKSKRD KKVSLTKTAK KGLELKQNLI EELRKCVDTY KYLFIFSVAN MRNSKLKDIR NAWKHSRMFF GKNKVMMVAL GRSPSDEYKD NLHQVSKRLR GEVGLLFTNR TKEEVNEWFT KYTEMDYARA GNKAAFTVSL DPGPLEQFPH SMEPQLRQLG LPTALKRGVV TLLSDYEVCK EGDVLTPEQA RVLKLFGYEM AEFKVTIKYM WDSQSGRFQQ MGDDLPESAS ESTEESDSED DD