Recombinant human Renalase protein
Renalase, also known as RNLS, is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney. It is also suggested that RNLS functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. A high concentration of catecholamines activate plasma RNLS and promotes its secretion and synthesis. Recombinant human RNLS protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Renalase, C10orf59, RENALASE
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
38.8 kDa (349aa)
Additionnal Information
References & Citations
Xu J., et al. (2007) Curr Poin Nephol Hypertens. 16:373-378.; ; Li G., et al. (2008) Circulation. 117:1277-1282.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_001026879
Uniprot Accession Number
Q5VYX0
Species
Human
AA Sequence
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