Recombinant human Renalase protein

Renalase, also known as RNLS, is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney. It is also suggested that RNLS functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. A high concentration of catecholamines activate plasma RNLS and promotes its secretion and synthesis. Recombinant human RNLS protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Renalase, C10orf59, RENALASE

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

38.8 kDa (349aa)

Additionnal Information

Renalase, Renalase, C10orf59, RENALASE, ATGP1732-10 µg, ATGP1732-20 µg, ATGP1732-50 µg, ATGP1732-100 µg, ATGP1732-250 µg, ATGP1732-500 µg, ATGP1732-1 mg, ATGP1732-10, ATGP1732-20, ATGP1732-50, ATGP1732-100, ATGP1732-250, ATGP1732-500, ATGP1732-1

References & Citations

Xu J., et al. (2007) Curr Poin Nephol Hypertens. 16:373-378.; ; Li G., et al. (2008) Circulation. 117:1277-1282.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_001026879

Uniprot Accession Number

Q5VYX0

Species

Human

AA Sequence

ALLRRQ TSGPLYLAVW DKAEDSGGRM TTACSPHNPQ CTADLGAQYI TCTPHYAKKH QRFYDELLAY GVLRPLSSPI EGMVMKEGDC NFVAPQGISS IIKHYLKESG AEVYFRHRVT QINLRDDKWE VSKQTGSPEQ FDLIVLTMPV PEILQLQGDI TTLISECQRQ QLEAVSYSSR YALGLFYEAG TKIDVPWAGQ YITSNPCIRF VSIDNKKRNI ESSEIGPSLV IHTTVPFGVT YLEHSIEDVQ ELVFQQLENI LPGLPQPIAT KCQKWRHSQV TNAAANCPGQ MTLHHKPFLA CGGDGFTQSN FDGCITSALC VLEALKNYI