Recombinant human TNFR1/TNFRSF1A protein

TNFRSF1A is a member of the tumor necrosis factor receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate the transcription factor NF-kB, mediate apoptosis, and function as a regulator of inflammation. It plays regulatory roles in the signal transduction mediated by the receptor. Recombinant human TNFRSF1A protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, Tumor necrosis factor-binding protein 1, TBPI, CS120a, p55, p60, TNF-R55, TNFR60

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

20.8 kDa (186aa)

Additionnal Information

TNF RI, TNFRSF1A, Tumor necrosis factor receptor superfamily member 1A, CD120a, FPF, p55, p55-R, p60, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, ATGP1730-10 µg, ATGP1730-20 µg, ATGP1730-50 µg, ATGP1730-100 µg, ATGP1730-250 µg, ATGP1730-500 µg, ATGP1730-1 mg, ATGP1730-10, ATGP1730-20, ATGP1730-50, ATGP1730-100, ATGP1730-250, ATGP1730-500, ATGP1730-1

References & Citations

Dunbar JD. et al. (1997) J Immunol. 158:4252-9.; ; Hsu H. et al. (1996) Cell. 84:299-308.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2M urea

Scientific Category

Immunology

NCBI Accession Number

NP_001056

Uniprot Accession Number

P19438

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMDSVCP QGKYIHPQNN SICCTKCHKG TYLYNDCPGP GQDTDCRECE SGSFTASENH LRHCLSCSKC RKEMGQVEIS SCTVDRDTVC GCRKNQYRHY WSENLFQCFN CSLCLNGTVH LSCQEKQNTV CTCHAGFFLR ENECVSCSNC KKSLECTKLC LPQIEN