Recombinant human SIX1 protein

SIX1, also known as homeobox protein SIX1, is a member of the SIX gene family. It encodes protein that is characterized by a divergent DNA-binding homeodomain and an upstream SIX domain, which may be involved both in determining DNA-binding specificity and in mediating protein-protein interactions. It has been shown to play roles in vertebrate and insect development or has been implicated in maintenance of the differentiated state of tissues. Recombinant human SIX1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Homeobox protein SIX1, BOS3, DFNA23, TIP39

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

34.7 kDa (308aa)

Additionnal Information

SIX1, homeobox protein SIX1, BOS3, DFNA23, TIP39, ATGP1728-10 µg, ATGP1728-20 µg, ATGP1728-50 µg, ATGP1728-100 µg, ATGP1728-250 µg, ATGP1728-500 µg, ATGP1728-1 mg, ATGP1728-10, ATGP1728-20, ATGP1728-50, ATGP1728-100, ATGP1728-250, ATGP1728-500, ATGP1728-1

References & Citations

Ruf RG. et al. (2004) Proc Natl Acad Sci u S A. 101 (21) :8090-8095.; ; Oliver G. et al. (1995) Development. 121 (3) :693-705.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2M urea

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_005973

Uniprot Accession Number

Q15475

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMSMLPS FGFTQEQVAC VCEVLQQGGN LERLGRFLWS LPACDHLHKN ESVLKAKAVV AFHRGNFREL YKILESHQFS PHNHPKLQQL WLKAHYVEAE KLRGRPLGAV GKYRVRRKFP LPRTIWDGEE TSYCFKEKSR GVLREWYAHN PYPSPREKRE LAEATGLTTT QVSNWFKNRR QRDRAAEAKE RENTENNNSS SNKQNQLSPL EGGKPLMSSS EEEFSPPQSP DQNSVLLLQG NMGHARSSNY SLPGLTASQP SHGLQTHQHQ LQDSLLGPLT SSLVDLGS