Recombinant human SH3BGRL3 protein
SH3 domain-binding glutamic acid-rich-like protein 3, also known as SH3BGRL3, is located to chromosome 1p34. 3-35 encodes for a small protein of 93 amino acids. SH3BGRL3 is the new member of thioredoxin (TRX) super family, whose posttranslational modified form was identified as tumor necrosis factor alpha (TNF-alpha) inhibitory protein. It may function as a regulator in all-trans retinoic acid-induced pathway. Recombinant human SH3BGRL3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
SH3 domain-binding glutamic acid-rich-like protein 3, SH3 domain-binding glutamic acid-rich-like protein 3, SH3BP-1, TIP-B1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
12.8 kDa (116aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Mazzocco M., et al. (2002) Gene. 291:233-9; ; Xu C., et al. (2005) FEBS Lett. 579: 2788-94.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol,1mM DTT
Scientific Category
Redox Proteins
NCBI Accession Number
NP_112576
Uniprot Accession Number
Q9H299
Species
Human
AA Sequence
MSGLRVY STSVTGSREI KSQQSEVTRI LDGKRIQYQL VDISQDNALR DEMRALAGNP KATPPQIVNG DQYCGDYELF VEAVEQNTLQ EFLKLA
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
PMAT, CT (ENT4, Equilibrative Nucleoside Transporter 4, FLJ34923, Solute Carrier Family 29 Member 4, Slc29a4) (APC) discontinued
