Recombinant human PDGF-D protein
Platelet-derived growth factor D, also known as PDGFD, plays an important role in wound healing. This protein induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. This protein can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix. Recombinant human PDGFD protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Platelet-derived growth factor D, IEGF, MSTP036, SCDGF-B, SCDGFB
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
16.6 kDa (146aa)
Additionnal Information
References & Citations
Bergsten E A., et al. (2001) Nat. Cell Biol. 3:512-516; ; uutela M., et al. (2004) Blood. 104:3198-3204
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_079484
Uniprot Accession Number
Q9GZP0
Species
Human
AA Sequence
SYHDR KSKVDLDRLN DDAKRYSCTP RNYSVNIREE LKLANVVFFP RCLLVQRCGG NCGCGTVNWR SCTCNSGKTV KKYHEVLQFE PGHIKRRGRA KTMALVDIQL DHHERCDCIC SSRPPR
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