Recombinant human TIAF1 protein

TGFB1-induced anti-apoptotic factor 1, also known as TIAF1, inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. This protein involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation. Recombinant human TIAF1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

TGFB1-induced anti-apoptotic factor 1, MAJN, SPR210

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

16.6 kDa (152aa)

Additionnal Information

TIAF1, TGFB1-induced anti-apoptotic factor 1, MAJN, SPR210, ATGP1708-10 µg, ATGP1708-20 µg, ATGP1708-50 µg, ATGP1708-100 µg, ATGP1708-250 µg, ATGP1708-500 µg, ATGP1708-1 mg, ATGP1708-10, ATGP1708-20, ATGP1708-50, ATGP1708-100, ATGP1708-250, ATGP1708-500, ATGP1708-1

References & Citations

Chang N.-S., et al. (1998) Biochem. Biophys. Res. Commun. 253:743-749; ; van der Leij J., et al. (2003) Transplantation. 75:2076-2082

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_004731

Uniprot Accession Number

O95411

Species

Human

AA Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSS PSSPFREQSF LCAAGDAGEE SRVQVLKNEV RRGSPVLLGW VEQAYADKCV CGPSAPPAPT PPSLSQRVMC NDLFKVNPFQ LQQFRADPST ASLLLCPGGL DHKLNLRGKA WG