Recombinant human MFAP4 protein

MFAP4, also as known as microfibrillar-associated protein 4, belongs to Fibrinogen protein family and contains 1 fibrinogen C-terminal domain. This protein has similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Recombinant human MFAP4 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Microfibrillar-associated protein 4, microfibrillar-associated protein 4, Microfibril associated glycoprotein 4, Microfibril-associated glycoprotein 4

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

29.2 kDa (259aa)

Additionnal Information

MFAP4, microfibrillar-associated protein 4, microfibrillar-associated protein 4, Microfibril associated glycoprotein 4, Microfibril-associated glycoprotein 4, ATGP1707-10 µg, ATGP1707-20 µg, ATGP1707-50 µg, ATGP1707-100 µg, ATGP1707-250 µg, ATGP1707-500 µg, ATGP1707-1 mg, ATGP1707-10, ATGP1707-20, ATGP1707-50, ATGP1707-100, ATGP1707-250, ATGP1707-500, ATGP1707-1

References & Citations

Lausen M, et al. (1999) J Biol Chem. 274 (45) :32234-40.; ; Zhao, Z., et al. (1995) Mol. Genet. 4: 589-597.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_002395

Uniprot Accession Number

P55083

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMVSGIR GDALERFCLQ QPLDCDDIYA QGYQSDGVYL IYPSGPSVPV PVFCDMTTEG GKWTVFQKRF NGSVSFFRGW NDYKLGFGRA DGEYWLGLQN MHLLTLKQKY ELRVDLEDFE NNTAYAKYAD FSISPNAVSA EEDGYTLFVA GFEDGGAGDS LSYHSGQKFS TFDRDQDLFV QNCAALSSGA FWFRSCHFAN LNGFYLGGSH LSYANGINWA QWKGFYYSLK RTEMKIRRA