Recombinant human MFAP4 protein
MFAP4, also as known as microfibrillar-associated protein 4, belongs to Fibrinogen protein family and contains 1 fibrinogen C-terminal domain. This protein has similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in cell adhesion or intercellular interactions. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Recombinant human MFAP4 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Microfibrillar-associated protein 4, microfibrillar-associated protein 4, Microfibril associated glycoprotein 4, Microfibril-associated glycoprotein 4
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
29.2 kDa (259aa)
Additionnal Information
References & Citations
Lausen M, et al. (1999) J Biol Chem. 274 (45) :32234-40.; ; Zhao, Z., et al. (1995) Mol. Genet. 4: 589-597.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_002395
Uniprot Accession Number
P55083
Species
Human
AA Sequence
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