Recombinant human UBTD2 protein

UBTD2, also known as DCuBP (dendritic cellderived ubiquitin-like protein), is a ubiquitin (ub) domain-containing protein first identified from dendritic cells, and is implicated in ubiquitination pathway. ubiquitin is the most well understood post-translation modifier, there is a growing family of ubiquitin-like proteins (uBLs) that modify cellular targets in a pathway. ubL proteins are involved in a variety of cellular processes, including DNA repair, protein sorting, apoptosis, protein degradation, cell division and autophagy. Recombinant human uBTD2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Ubiquitin domain containing 2, DCuBP, SB72

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

28.6 kDa (257aa) confirmed by MALDI-TOF

Additionnal Information

UBTD2, ubiquitin domain containing 2, DCuBP, SB72, ATGP1697-10 µg, ATGP1697-20 µg, ATGP1697-50 µg, ATGP1697-100 µg, ATGP1697-250 µg, ATGP1697-500 µg, ATGP1697-1 mg, ATGP1697-10, ATGP1697-20, ATGP1697-50, ATGP1697-100, ATGP1697-250, ATGP1697-500, ATGP1697-1

References & Citations

Song AX, et al. (2010) Protein Sci. 19 (5) :1104-9.; ; Gao, Y.G., et al. (2005) Protein Sci. 14: 2044-2050.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT

Scientific Category

Ubiquitination

NCBI Accession Number

NP_689490

Uniprot Accession Number

Q8WUN7

Species

Human

AA Sequence

MGGCVGA QHDSSGSLNE NSEGTGVALG RNQPLKKEKP KWKSDYPMTD GQLRSKRDEF WDTAPAFEGR KEIWDALKAA AHAFESNDHE LAQAIIDGAN ITLPHGALTE CYDELGNRYQ LPVYCLAPPI NMIEEKSDIE TLDIPEPPPN SGYECQLRLR LSTGKDLKLV VRSTDTVFHM KRRLHAAEGV EPGSQRWFFS GRPLTDKMKF EELKIPKDYV VQVIVSQPVQ NPTPVEN