Recombinant human NDRG2 protein
NDRG2, also known as SYLD, is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Expressed at high levels in heart, brain, dendritic cells, salivary gland and skeletal muscle and at lower levels in liver and kidney, NDRG2 is thought to be involved in dendritic and neuronal cell differentiation and outgrowth. It is found in brain lesions of Alzheimer Disease (AD) -affected patients and is thought to be associated with the progression of AD. Recombinant human NDRG2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Protein NDRG2, SYLD
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
41.8 kDa (381aa)
Additionnal Information
References & Citations
Deng Y., et al. (2003) Int J Cancer. 106:342-347.; ; Lusis E A., et al. (2005) Cancer Res. 65:7121-7126.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea,10% glycerol, 0.1M NaCl
Scientific Category
Cancer
NCBI Accession Number
NP_963832
Uniprot Accession Number
Q9UN36
Species
Human
AA Sequence
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
