Recombinant human NDRG2 protein

NDRG2, also known as SYLD, is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Expressed at high levels in heart, brain, dendritic cells, salivary gland and skeletal muscle and at lower levels in liver and kidney, NDRG2 is thought to be involved in dendritic and neuronal cell differentiation and outgrowth. It is found in brain lesions of Alzheimer Disease (AD) -affected patients and is thought to be associated with the progression of AD. Recombinant human NDRG2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Protein NDRG2, SYLD

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

41.8 kDa (381aa)

Additionnal Information

NDRG2, protein NDRG2, SYLD, ATGP1692-10 µg, ATGP1692-20 µg, ATGP1692-50 µg, ATGP1692-100 µg, ATGP1692-250 µg, ATGP1692-500 µg, ATGP1692-1 mg, ATGP1692-10, ATGP1692-20, ATGP1692-50, ATGP1692-100, ATGP1692-250, ATGP1692-500, ATGP1692-1

References & Citations

Deng Y., et al. (2003) Int J Cancer. 106:342-347.; ; Lusis E A., et al. (2005) Cancer Res. 65:7121-7126.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea,10% glycerol, 0.1M NaCl

Scientific Category

Cancer

NCBI Accession Number

NP_963832

Uniprot Accession Number

Q9UN36

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMAELQE VQITEEKPLL PGQTPEAAKT HSVETPYGSV TFTVYGTPKP KRPAILTYHD VGLNYKSCFQ PLFQFEDMQE IIQNFVRVHV DAPGMEEGAP VFPLGYQYPS LDQLADMIPC VLQYLNFSTI IGVGVGAGAY ILARYALNHP DTVEGLVLIN IDPNAKGWMD WAAHKLTGLT SSIPEMILGH LFSQEELSGN SELIQKYRNI ITHAPNLDNI ELYWNSYNNR RDLNFERGGD ITLRCPVMLV VGDQAPHEDA VVECNSKLDP TQTSFLKMAD SGGQPQLTQP GKLTEAFKYF LQGMGYMASS CMTRLSRSRT ASLTSAASVD GNRSRSRTLS QSSESGTLSS GPPGHTMEVS C