Recombinant human DYNLT3 protein

DYNLT3 is a member of a subclass of dynein light chains. This protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. It may be important for binding dynein to specific cargos including the spindle checkpoint protein BuB3. DYNLT3 may also function independently of dynein as a transcriptional modulator. Recombinant human DYNLT3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Dynein light chain Tctex-type 3, RP3; TCTE1L; TCTEX1L

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

15.5 kDa (139aa) confirmed by MALDI-TOF

Additionnal Information

DYNLT3, Dynein light chain Tctex-type 3, RP3; TCTE1L; TCTEX1L, ATGP1691-10 µg, ATGP1691-20 µg, ATGP1691-50 µg, ATGP1691-100 µg, ATGP1691-250 µg, ATGP1691-500 µg, ATGP1691-1 mg, ATGP1691-10, ATGP1691-20, ATGP1691-50, ATGP1691-100, ATGP1691-250, ATGP1691-500, ATGP1691-1

References & Citations

Yeh TY, et al. (2005) . J Cell Sci. 1; ;118 (Pt 15) :3431-43.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_006511

Uniprot Accession Number

P51808

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMEEYHRH CDEVGFNAEE AHNIVKECVD GVLGGEDYNH NNINQWTASI VEQSLTHLVK LGKAYKYIVT CAVVQKSAYG FHTASSCFWD TTSDGTCTVR WENRTMNCIV NVFAIAIVL