Recombinant human TULP1 protein

Tubby-related protein 1, also known as TuLP1, is a member of the TuLP family of four proteins (TuB and TuLP1, -2, and -3), characterized structurally by the highly conserved C-terminal half of the protein. In the retina, TuLP1 is found exclusively in photoreceptor cells, localizing primarily in the inner segments and connecting cilium and to a lesser extent in the perinuclear cytoplasm and synaptic termini. Recombinant human TuLP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Tubby-related protein 1, LCA15, RP14, TuBL1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

31.1 kDa (276aa) confirmed by MALDI-TOF

Additionnal Information

TULP1, Tubby-related protein 1, LCA15, RP14, TuBL1, ATGP1680-10 µg, ATGP1680-20 µg, ATGP1680-50 µg, ATGP1680-100 µg, ATGP1680-250 µg, ATGP1680-500 µg, ATGP1680-1 mg, ATGP1680-10, ATGP1680-20, ATGP1680-50, ATGP1680-100, ATGP1680-250, ATGP1680-500, ATGP1680-1

References & Citations

Xi Q., et al. (2005) Invest. Ophthalmol. Vis. Sci. 46:4754-4761; ; Caberoy N.B., et al. (2010) Exp. Cell Res. 316:245-257

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 5mM DTT, 2mM EDTA

Scientific Category

Neuroscience

NCBI Accession Number

NP_003313.3

Uniprot Accession Number

O00294

Species

Human

AA Sequence

EPREFVL RPAPQGRTVR CRLTRDKKGM DRGMYPSYFL HLDTEKKVFL LAGRKRKRSK TANYLISIDP TNLSRGGENF IGKLRSNLLG NRFTVFDNGQ NPQRGYSTNV ASLRQELAAV IYETNVLGFR GPRRMTVIIP GMSAENERVP IRPRNASDGL LVRWQNKTLE SLIELHNKPP VWNDDSGSYT LNFQGRVTQA SVKNFQIVHA DDPDYIVLQF GRVAEDAFTL DYRYPLCALQ AFAIALSSFD GKLACE