What is the catalog number for Recombinant human TBCC protein?

The catalog number for Recombinant human TBCC protein is ATGP1673-250.

What sizes are available for Recombinant human TBCC protein?

Recombinant human TBCC protein is available in the following size(s): 250 µg.

Is Recombinant human TBCC protein in stock?

Recombinant human TBCC protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human TBCC protein

TBCC (tubulin folding cofactor C) belongs to the TBCC family. It is plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration. Cofactor C is one of four proteins (cofactors A, D, E and C) involved in the pathway leading to correctly folded b-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing b-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/b-tubulin complex; interaction with cofactor C then causes the release of b-tubulin polypeptides. Recombinant human TBCC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Tubulin-specific chaperone C, CFC, tubulin folding cofactor C

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

41.7 kDa (369aa) confirmed by MALDI-TOF

Additionnal Information

TBCC, Tubulin-specific chaperone C, CFC, tubulin folding cofactor C, ATGP1673-10 µg, ATGP1673-20 µg, ATGP1673-50 µg, ATGP1673-100 µg, ATGP1673-250 µg, ATGP1673-500 µg, ATGP1673-1 mg, ATGP1673-10, ATGP1673-20, ATGP1673-50, ATGP1673-100, ATGP1673-250, ATGP1673-500, ATGP1673-1

References & Citations

Goncalves J., et al. (2010) EMBO Rep. 11:194-200; ; Lewis SA, et al. (1996) . J. Cell Biol. 132 (1-2) : 1-4.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_003183

Uniprot Accession Number

Q15814

Species

Human

AA Sequence

MESVSCS AAAVRTGDME SQRDLSLVPE RLQRREQERQ LEVERRKQKR QNQEVEKENS HFFVATFARE RAAVEELLER AESVERLEEA ASRLQGLQKL INDSVFFLAA YDLRQGQEAL ARLQAALAER RRGLQPKKRF AFKTRGKDAA SSTKVDAAPG IPPAVESIQD SPLPKKAEGD LGPSWVCGFS NLESQVLEKR ASELHQRDVL LTELSNCTVR LYGNPNTLRL TKAHSCKLLC GPVSTSVFLE DCSDCVLAVA CQQLRIHSTK DTRIFLQVTS RAIVEDCSGI QFAPYTWSYP EIDKDFESSG LDRSKNNWND VDDFNWLARD MASPNWSILP EEERNIQWD