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Recombinant human SYCE3 protein

SYCE3 (synaptonemal complex central element protein 3) is major component of the transverse central element of synaptonemal complexes (SCS) . The synaptonemal complex is a protein structure that forms between homologous chromosomes (two pairs of sister chromatids) during meiosis and that is thought to mediate chromosome pairing, synapsis, and recombination (crossing-over) . This protein required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Recombinant human SYCE3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Synaptonemal complex central element protein 3, testis highly expressed protein 2, C22orf41, chromosome 22 open reading frame 41, THEG-2, THEG2, SYCE-3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

12.8 kDa (108aa) confirmed by MALDI-TOF

Additionnal Information

SYCE3, synaptonemal complex central element protein 3, testis highly expressed protein 2, C22orf41, chromosome 22 open reading frame 41, THEG-2, THEG2, SYCE-3, ATGP1672-10 µg, ATGP1672-20 µg, ATGP1672-50 µg, ATGP1672-100 µg, ATGP1672-250 µg, ATGP1672-500 µg, ATGP1672-1 mg, ATGP1672-10, ATGP1672-20, ATGP1672-50, ATGP1672-100, ATGP1672-250, ATGP1672-500, ATGP1672-1

References & Citations

Schramm S, et al. (2011) PLoS Genet, May; ;7 (5) :e1002088

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 2mM DTT

Scientific Category

Cell Cycle

NCBI Accession Number

NP_001116697

Uniprot Accession Number

A1L190

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MDDADPEERN YDNMLKMLSD LNKDLEKLLE EMEKISVQAT WMAYDMVVMR TNPTLAESMR RLEDAFVNCK EEMEKNWQEL LHETKQRL

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