Recombinant human ITGB1BP3 protein

Nicotinamide riboside kinase 2, also known as ITGB1BP3, belongs to the uridine kinase family and NRK subfamily. ITGB1BP3 is found at lower levels in heart and is downregulated during myoblast differentiation. ITGB1BP3 catalyzes the phosphorylation of nicotinic acid riboside and nicotinamide riboside to form nicotinic acid mononucleotide and nicotinamide mononucleotide. Recombinant human ITGB1BP3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Nicotinamide riboside kinase 2, MIBP, NRK2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

28.4 kDa (253aa) confirmed by MALDI-TOF

Additionnal Information

ITGB1BP3, Nicotinamide riboside kinase 2, MIBP, NRK2, ATGP1670-10 µg, ATGP1670-20 µg, ATGP1670-50 µg, ATGP1670-100 µg, ATGP1670-250 µg, ATGP1670-500 µg, ATGP1670-1 mg, ATGP1670-10, ATGP1670-20, ATGP1670-50, ATGP1670-100, ATGP1670-250, ATGP1670-500, ATGP1670-1

References & Citations

Li J., et al. (1999) J Cell Biol. 147: 1391-1398; ; Li J., et al. (2003) Dev Biol. 261: 209-219.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol,1mM DTT

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_733778

Uniprot Accession Number

Q9NPI5

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMKLIVGI GGMTNGGKTT LTNSLLRALP NCCVIHQDDF FKPQDQIAVG EDGFKQWDVL ESLDMEAMLD TVQAWLSSPQ KFARAHGVSV QPEASDTHIL LLEGFLLYSY KPLVDLYSRR YFLTVPYEEC KWRRSTRNYT VPDPPGLFDG HVWPMYQKYR QEMEANGVEV VYLDGMKSRE ELFREVLEDI QNSLLNRSQE SAPSPARPAR TQGPGRGCGH RTARPAASQQ DSM