Recombinant human ARH3/ADPRS protein

ADP-ribosylhydrolase like 2, also known as ADPRHL2, is a member of the ADP-ribosylglycohydrolase family. Expressed ubiquitously, ADPRHL2 uses magnesium as a cofactor to catalyze the hydrolysis of poly (ADP-ribose) that is synthesized after DNA damage. Also, ADPRHL2 plays an important role in the maintenance of normal neuronal cell function. Recombinant human ADPRHL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

ADP-ribosylhydrolase like 2, ARH3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

41.5 kDa (387aa) confirmed by MALDI-TOF

Additionnal Information

ADPRHL2, ADP-ribosylhydrolase like 2, ARH3, ATGP1665-10 µg, ATGP1665-20 µg, ATGP1665-50 µg, ATGP1665-100 µg, ATGP1665-250 µg, ATGP1665-500 µg, ATGP1665-1 mg, ATGP1665-10, ATGP1665-20, ATGP1665-50, ATGP1665-100, ATGP1665-250, ATGP1665-500, ATGP1665-1

References & Citations

Kernstock S., et al. (2006) Sect F Struct Biol Cryst Commun. 62: 224-227; ; Mueller Dieckmann C., et al. (2006) Proc Natl Acad Sci uSA. 103: 15026-15031.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 30% glycerol,1mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_060295

Uniprot Accession Number

Q9NX46

Species

Human

AA Sequence

MAAAAM AAAAGGGAGA ARSLSRFRGC LAGALLGDCV GSFYEAHDTV DLTSVLRHVQ SLEPDPGTPG SERTEALYYT DDTAMARALV QSLLAKEAFD EVDMAHRFAQ EYKKDPDRGY GAGVVTVFKK LLNPKCRDVF EPARAQFNGK GSYGNGGAMR VAGISLAYSS VQDVQKFARL SAQLTHASSL GYNGAILQAL AVHLALQGES SSEHFLKQLL GHMEDLEGDA QSVLDARELG MEERPYSSRL KKIGELLDQA SVTREEVVSE LGNGIAAFES VPTAIYCFLR CMEPDPEIPS AFNSLQRTLI YSISLGGDTD TIATMAGAIA GAYYGMDQVP ESWQQSCEGY EETDILAQSL HRVFQKS