Recombinant human TMDP/DUSP13 protein
DUSP13 (Dual specificity phosphatase 13) belongs to the protein-tyrosine phosphatase family. It cooperates with protein kinases to regulate cell proliferation and differentiation. DUSP13 is involved in the regulation of meiosis and/or differentiation of testicular germ cells during spermatogenesis. This protein exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues of myelin basic protein, with similar specific activities in vitro. Recombinant human DUSP13 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
24.7 kDa (222aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Chen H.-H., et al. (2004) J. Biol. Chem. 279:41404-41413; ; Katagiri C, et al. (2011) Mol Cell Biochem. 352 (1-2) :155-62.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_057448.3
Uniprot Accession Number
Q9UII6
Species
Human
AA Sequence
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