Recombinant human HBXIP/LAMTOR5 protein

Hepatitis B virus x interacting protein, also known as HBXIP, was originally identified by its ability to form a complex with the C-terminus of hepatitis B virus X (HBX) protein. HBXIP negatively regulates the activity of HBX and alters the replicative life cycle of the virus. In addition, HBXIP is involved in bipolar spindle formation and regulates centrosome dynamics and cytokinesis in cells, possibly through an interaction with Dynein light chain. Recombinant human HBXIP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Hepatitis B virus x interacting protein, XIP

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

20.7 kDa (197aa) confirmed by MALDI-TOF

Additionnal Information

HBXIP, Hepatitis B virus x interacting protein, XIP, ATGP1650-10 µg, ATGP1650-20 µg, ATGP1650-50 µg, ATGP1650-100 µg, ATGP1650-250 µg, ATGP1650-500 µg, ATGP1650-1 mg, ATGP1650-10, ATGP1650-20, ATGP1650-50, ATGP1650-100, ATGP1650-250, ATGP1650-500, ATGP1650-1

References & Citations

Zhang X., et al. (2005) J Med Virol. 77: 374-381; ; Melegari M., et al. (1998) J Virol. 72: 1737-1743.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM EDTA

Scientific Category

Immunology

NCBI Accession Number

NP_006393

Uniprot Accession Number

O43504

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMEPGAG HLDGHRAGSP SLRQALCDGS AVMFSSKERG RCTVINFVPL EAPLRSTPRS RQVTEACGGE GRAVPLGSEP EWSVGGMEAT LEQHLEDTMK NPSIVGVLCT DSQGLNLGCR GTLSDEHAGV ISVLAQQAAK LTSDPTDIPV VCLESDNGNI MIQKHDGITV AVHKMAS