Recombinant human HOPX protein

HOPX, also known as homeodomain-only protein, acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. This protein prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Recombinant human HOPX protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Homeodomain-only protein, CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

10.8 kDa (97aa) confirmed by MALDI-TOF

Additionnal Information

HOPX, Homeodomain-only protein, CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO, ATGP1639-10 µg, ATGP1639-20 µg, ATGP1639-50 µg, ATGP1639-100 µg, ATGP1639-250 µg, ATGP1639-500 µg, ATGP1639-1 mg, ATGP1639-10, ATGP1639-20, ATGP1639-50, ATGP1639-100, ATGP1639-250, ATGP1639-500, ATGP1639-1