Recombinant human LDOC1L/RTL6 protein

Leucine zipper, down-regulated in cancer 1-like, also known as LDOC1L, belongs to the LDOC1 family. LDOC1 is a nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. LDOC1L is thought to regulate the transcriptional response mediated by the nuclear factor kB (NFkB) . Recombinant human LDOC1L protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Protein LDOC1L, dJ1033E15.2, Mar6, Mart6

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

28.7 kDa (263aa) confirmed by MALDI-TOF

Additionnal Information

DJ1033E15.2, LDOC1L, Mar 6, Mar6, Mar-6, Mart 6, Mart6, Mart-6, Protein LDOC1L, ATGP1629-10 µg, ATGP1629-20 µg, ATGP1629-50 µg, ATGP1629-100 µg, ATGP1629-250 µg, ATGP1629-500 µg, ATGP1629-1 mg, ATGP1629-010, ATGP1629-020, ATGP1629-050, ATGP1629-100, ATGP1629-250, ATGP1629-500, ATGP1629-01M

References & Citations

Nagasaki K., et al. (1999) Cancer Lett. 140: 227-234; ; Nagasaki K., et al. (2003) J Cancer. 105: 454-458.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol, 2mM DTT, 0.1mM PMSF, 1mM EDTA

Scientific Category

Signal Transduction

NCBI Accession Number

NP_115663

Uniprot Accession Number

Q6ICC9

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMVQPQT SKAESPALAA SPNAQMDDVI DTLTSLRLTN SALRREASTL RAEKANLTNM LESVMAELTL LRTRARIPGA LQITPPISSI TSNGTRPMTT PPTSLPEPFS GDPGRLAGFL MQMDRFMIFQ ASRFPGEAER VAFLVSRLTG EAEKWAIPHM QPDSPLRNNY QGFLAELRRT YKSPLRHARR AQIRKTSASN RAVRERQMLC RQLASAGTGP CPVHPASNGT SPAPALPARA RNL