Recombinant human LDOC1L/RTL6 protein
Leucine zipper, down-regulated in cancer 1-like, also known as LDOC1L, belongs to the LDOC1 family. LDOC1 is a nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. LDOC1L is thought to regulate the transcriptional response mediated by the nuclear factor kB (NFkB) . Recombinant human LDOC1L protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Protein LDOC1L, dJ1033E15.2, Mar6, Mart6
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
28.7 kDa (263aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Nagasaki K., et al. (1999) Cancer Lett. 140: 227-234; ; Nagasaki K., et al. (2003) J Cancer. 105: 454-458.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol, 2mM DTT, 0.1mM PMSF, 1mM EDTA
Scientific Category
Signal Transduction
NCBI Accession Number
NP_115663
Uniprot Accession Number
Q6ICC9
Species
Human
AA Sequence
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