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Recombinant human Kallikrein 5/KLK5 protein

Kallikrein-5, also known as KLK5, belongs to the serine protease family of proteolytic enzymes. The human KLK gene family consists of 15 serine proteases. It is expressed in a variety of tissues including salivary gland, stomach, uterus, lung, thymus, prostate, colon, brain, thyroid, and trachea. The function of the other members of KLK gene family is currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. Recombinant human KLK5 protein, fused to His-tag at N-terminus, was expressed in E. coli

Product Specifications

Product Name Alternative

Kallikrein-5, KLK5, KLKL2, SCTE, Kallikrein related peptidase 5, Kallikrein-like protein 2, Stratum corneum tryptic enzyme

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

27.8 kDa (252aa)

Additionnal Information

Kallikrein-5, KLK5, KLKL2, KLK-L2, SCTE, Kallikrein related peptidase 5, Kallikrein-like protein 2, Stratum corneum tryptic enzyme, ATGP1626-10 µg, ATGP1626-20 µg, ATGP1626-50 µg, ATGP1626-100 µg, ATGP1626-250 µg, ATGP1626-500 µg, ATGP1626-1 mg, ATGP1626-010, ATGP1626-020, ATGP1626-050, ATGP1626-100, ATGP1626-250, ATGP1626-500, ATGP1626-01M

References & Citations

Clements J., et al. (2001) Biol Chem. 382:5-14.; ; Diamandis E P., et al. (2000) Trends Endocrinol Metab. 11:54-60.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_001070960.1

Uniprot Accession Number

Q9Y337

Species

Human

AA Sequence

IINGS DCDMHTQPWQ AALLLRPNQL YCGAVLVHPQ WLLTAAHCRK KVFRVRLGHY SLSPVYESGQ QMFQGVKSIP HPGYSHPGHS NDLMLIKLNR RIRPTKDVRP INVSSHCPSA GTKCLVSGWG TTKSPQVHFP KVLQCLNISV LSQKRCEDAY PRQIDDTMFC AGDKAGRDSC QGDSGGPVVC NGSLQGLVSW GDYPCARPNR PGVYTNLCKF TKWIQETIQA NS

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