Recombinant human Kallikrein 5/KLK5 protein
Kallikrein-5, also known as KLK5, belongs to the serine protease family of proteolytic enzymes. The human KLK gene family consists of 15 serine proteases. It is expressed in a variety of tissues including salivary gland, stomach, uterus, lung, thymus, prostate, colon, brain, thyroid, and trachea. The function of the other members of KLK gene family is currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. Recombinant human KLK5 protein, fused to His-tag at N-terminus, was expressed in E. coli
Product Specifications
Product Name Alternative
Kallikrein-5, KLK5, KLKL2, SCTE, Kallikrein related peptidase 5, Kallikrein-like protein 2, Stratum corneum tryptic enzyme
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
27.8 kDa (252aa)
Additionnal Information
References & Citations
Clements J., et al. (2001) Biol Chem. 382:5-14.; ; Diamandis E P., et al. (2000) Trends Endocrinol Metab. 11:54-60.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol
Scientific Category
Cytoskeleton
NCBI Accession Number
NP_001070960.1
Uniprot Accession Number
Q9Y337
Species
Human
AA Sequence
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