Recombinant human RANGRF protein
RANGRF is a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1. 5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. Recombinant human RANGRF protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
RAN guanine nucleotide release factor, HSPC165, HSPC236, MOG1, RANGNRF
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23 kDa (210aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Olesen, M.S., et al. (2011) Can J Cardiol 27 (4), 523; ; Kattygnarath, D., et al. (2011) Circ Cardiovasc Genet 4 (3), 261-268.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.15M NaCl, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_057576
Uniprot Accession Number
Q9HD47
Species
Human
AA Sequence
Frequently Asked Questions
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