Recombinant human OVCA2 protein
Ovarian tumor suppressor candidate 2, also known as OVCA2, belongs to the uPF0483 family. It is ubiquitously expressed and its expression is regulated by retinoids. OVCA2 interacts with apoptosis-related protein Bag-1, indicating that this protein may participate in cell proliferation. Due to its structural and catalytic characteristics, OVCA2 is thought to act as a serine-hydrolase and, because of its reduced expression in ovarian and other tumor cell lines, it may play a role in tumor suppression. Recombinant human OVCA2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Ovarian tumor suppressor candidate 2, Ovarian cancer-associated gene 2 protein
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
26.9 kDa (251aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Azizi A A., et al. (2006) Cancer Lett. 241 (2) :235-49.; ; Prowse A H., et al. (2002) Int J Cancer. 99 (2) : 185-92.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_543012
Uniprot Accession Number
Q8WZ82
Species
Human
AA Sequence
Frequently Asked Questions
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