Recombinant human APIP protein
APIP, also known as probable methylthioribulose-1-phosphate dehydratase, catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2, 3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) . It has an anti-apoptotic function and prevents muscle ischemic damage. This protein inhibits the cytochrome c-dependent and APAF1-mediated cell death. Recombinant human APIP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Probable methylthioribulose-1-phosphate dehydratase, APIP2, CGI-29, CGI29, dJ179L10.2, MMRP19
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
29.7 kDa (266aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Cho D.-H., et al. (2004) J. Biol. Chem. 279:39942-39950; ; Lai C.-H., et al. (2000) Genome Res. 10:703-713
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Scientific Category
Apoptosis
NCBI Accession Number
NP_057041
Uniprot Accession Number
Q96GX9
Species
Human
AA Sequence
Frequently Asked Questions
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