Recombinant human Epimorphin/Syntaxin 2 protein

Syntaxin-2, also known as STX2, belongs to thesyntaxin/epimorphin family of proteins. Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. STX2 is a t-SNARE that localizes to the apical plasma membrane and intracellular vesicular structures. Also, STX2, along with SNAP-23, is required for regulated surfactant secretion. Recombinant human STX2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Syntaxin-2, EPIM, EPM, STX2A, STX2B, STX2C

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

33.6 kDa (289aa) confirmed by MALDI-TOF

Additionnal Information

Epimorphin, Syntaxin2, Syntaxin-2, EPIM, EPM, STX2A, STX2B, STX2C, ATGP1613-10 µg, ATGP1613-20 µg, ATGP1613-50 µg, ATGP1613-100 µg, ATGP1613-250 µg, ATGP1613-500 µg, ATGP1613-1 mg, ATGP1613-10, ATGP1613-20, ATGP1613-50, ATGP1613-100, ATGP1613-250, ATGP1613-500, ATGP1613-1

References & Citations

Abonyo BO., et al. (2004) Biochemistry. 43:3499-3506.; ; Bennett M K., et al. (1993) Cell. 74: 863-873.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 50% glycerol,1mM DTT

Scientific Category

Neuroscience

NCBI Accession Number

NP_919337

Uniprot Accession Number

P32856

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMMRDRL PDLTACRKND DGDTVVVVEK DHFMDDFFHQ VEEIRNSIDK ITQYVEEVKK NHSIILSAPN PEGKIKEELE DLNKEIKKTA NKIRAKLKAI EQSFDQDESG NRTSVDLRIR RTQHSVLSRK FVEAMAEYNE AQTLFRERSK GRIQRQLEIT GRTTTDDELE EMLESGKPSI FTSDIISDSQ ITRQALNEIE SRHKDIMKLE TSIRELHEMF MDMAMFVETQ GEMINNIERN VMNATDYVEH AKEETKKAIK YQSKARRKK