Recombinant human Epimorphin/Syntaxin 2 protein
Syntaxin-2, also known as STX2, belongs to thesyntaxin/epimorphin family of proteins. Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. STX2 is a t-SNARE that localizes to the apical plasma membrane and intracellular vesicular structures. Also, STX2, along with SNAP-23, is required for regulated surfactant secretion. Recombinant human STX2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Syntaxin-2, EPIM, EPM, STX2A, STX2B, STX2C
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
33.6 kDa (289aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Abonyo BO., et al. (2004) Biochemistry. 43:3499-3506.; ; Bennett M K., et al. (1993) Cell. 74: 863-873.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 50% glycerol,1mM DTT
Scientific Category
Neuroscience
NCBI Accession Number
NP_919337
Uniprot Accession Number
P32856
Species
Human
AA Sequence
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