Recombinant human HSCB protein
HSCB belongs to the hscB family and contains 1 J domain. This protein is expressed in lung, brain, stomach, spleen, ovary, testis, liver, muscle and heart and localized to mitochondria and cytoplasm. It may act as a co-chaperone in iron-sulfur cluster assembly in mitochondria, Interacts with ISCu and HSPA9. Recombinant human HSCB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
HscB iron-sulfur cluster co-chaperone homolog (E.coli), dJ366L4.2, DNAJC20, HSC20, JAC1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
26.7 kDa (231aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Sun G., et al. (2003) J. Hum. Genet. 48, 415-419; ; Bitto E., et al. (2008) J. Biol. Chem. 283, 30184-30192
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15M NaCl
Scientific Category
Metabolism
NCBI Accession Number
NP_741999
Uniprot Accession Number
Q8IWL3
Species
Human
AA Sequence
Frequently Asked Questions
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