Recombinant human Annexin A8-like protein 1/ANXA8L1 protein

Annexin A8-like 2, also known as ANXA8L2, is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. ANXA8L2 is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. Overexpression of ANXA8L2 has been associated with acute myelocytic leukemia. Recombinant human ANXA8L2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Annexin A8-like protein 1, ANXA8L2, Annexin A8-like protein 2, bA145E20.2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

39.4 kDa (351aa) confirmed by MALDI-TOF

Additionnal Information

Annexin A8 like protein 1, Annexin A8 like protein 2, Annexin A8-like protein 1, Annexin A8-like protein 2, Annexin A8-like protein1, Annexin A8-like protein2, ANXA 8, ANXA8, ANXA8L2, bA145E20.2, ATGP1598-10 µg, ATGP1598-20 µg, ATGP1598-50 µg, ATGP1598-100 µg, ATGP1598-250 µg, ATGP1598-500 µg, ATGP1598-1 mg, ATGP1598-010, ATGP1598-020, ATGP1598-050, ATGP1598-100, ATGP1598-250, ATGP1598-500, ATGP1598-01M

References & Citations

Liu J H., et al. (1994) Leuk Lymph. 13:381-386.; ; Chan H C., et al. (1994) J Biol Chem. 269:32464-32468.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_001621

Uniprot Accession Number

Q5VT79

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMAWWKA WIEQEGVTVK SSSHFNPDPD AETLYKAMKG IGTNEQAIID VLTKRSNTQR QQIAKSFKAQ FGKDLTETLK SELSGKFERL IVALMYPPYR YEAKELHDAM KGLGTKEGVI IEILASRTKN QLREIMKAYE EDYGSSLEED IQADTSGYLE RILVCLLQGS RDDVSSFVDP ALALQDAQDL YAAGENIRGT DEMKFITILC TRSATHLLRV FEEYEKIANK SIEDSIKSET HGSLEEAMLT VVKCTQNLHS YFAERLYYAM KGAGTRDGTL IRNIVSRSEI DLNLIKCHFK KMYGKTLSSM IMEDTSGDYK NALLSLVGSD P