Recombinant human FUBP1 protein
FUBP1 is a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase. Recombinant human FUBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Far upstream element (FuSE) binding protein 1, FBP, FuBP
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by BCA assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
20.8 kDa (195aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Zheng, Y., et al. (2011) Int. J. Biochem. Cell Biol. 43 (11), 1641-1648; ; Neubauer, A., et al. (2011) Exp. Hematol. 39 (10), 1030-1042.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15M NaCl
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_003893.2
Uniprot Accession Number
Q96AE4
Species
Human
AA Sequence
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