Recombinant human STK16 protein
STK16, also known as serine/threonine-protein kinase 16, is a membrane-associated protein kinase that phosphorylates on serine and threonine residues. STK16 may be involved in secretory vesicle trafficking or intracellular signaling. Also this protein may have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. It able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins. Recombinant human STK16 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Serine/threonine-protein kinase 16, KRCT, MPSK, PKL12, TSF1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
37.2 kDa (329aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Berson A.E., et al. (1999) Biochem. Biophys. Res. Commun. 259:533-538; ; Eswaran J., et al. (2009) Structure. 16:115-124
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001008910
Uniprot Accession Number
O75716
Species
Human
AA Sequence
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