Recombinant human MAGEA6 protein
MAGEA6 is a member of the MAGEA family, which directs the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes (CTL) . The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. Recombinant human MAGEA6 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Melanoma-associated antigen 6, CT1.6, MAGE-3b, MAGE3B, MAGE6
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
35.9 kDa (322aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Kobayasshi Y., et al. (2000) J Hepatol. 32:612-617.; ; Klein C., et al. (2000) J Exp Med. 191: 1699-1708.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_005354.1
Uniprot Accession Number
P43360
Species
Human
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