Recombinant human Hematopoietic Prostaglandin D Synthase/HPGDS protein

HPGDS, also known as GSTS, is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. Recombinant human HPGDS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Hematopoietic prostaglandin D synthase, GSTS, PGDS, H-PGDS, PGD2, GSTS1-1, GSTS1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

25.9 kDa (223aa) confirmed by MALDI-TOF

Additionnal Information

Hematopoietic prostaglandin D synthase, GSTS, PGDS, H-PGDS, PGD2, GSTS1-1, GSTS1, HPGDS, H PGDS, ATGP1557-10 µg, ATGP1557-20 µg, ATGP1557-50 µg, ATGP1557-100 µg, ATGP1557-250 µg, ATGP1557-500 µg, ATGP1557-1 mg, ATGP1557-010, ATGP1557-020, ATGP1557-050, ATGP1557-100, ATGP1557-250, ATGP1557-500, ATGP1557-01M

References & Citations

Welter, H., et al. (2011) Fertil. Steril. 96 (2), 309-313; ; uchida, Y, et al. (2010) J. Inorg. Biochem. 104 (3), 331-340

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15M NaCl,1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_055300

Uniprot Accession Number

O60760

Species

Human

AA Sequence

MPNYKL TYFNMRGRAE IIRYIFAYLD IQYEDHRIEQ ADWPEIKSTL PFGKIPILEV DGLTLHQSLA IARYLTKNTD LAGNTEMEQC HVDAIVDTLD DFMSCFPWAE KKQDVKEQMF NELLTYNAPH LMQDLDTYLG GREWLIGNSV TWADFYWEIC STTLLVFKPD LLDNHPRLVT LRKKVQAIPA VANWIKRRPQ TKL