Recombinant human HOMER3 protein

HOMER3, also known as homer protein homolog 3, is a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. Recombinant human HOMER3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Homer protein homolog 3, HOMER-3, VESL3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

42.5 kDa (386aa) confirmed by MALDI-TOF

Additionnal Information

HOMER3, Homer protein homolog 3, HOMER-3, VESL3, ATGP1548-10 µg, ATGP1548-20 µg, ATGP1548-50 µg, ATGP1548-100 µg, ATGP1548-250 µg, ATGP1548-500 µg, ATGP1548-1 mg, ATGP1548-10, ATGP1548-20, ATGP1548-50, ATGP1548-100, ATGP1548-250, ATGP1548-500, ATGP1548-1

References & Citations

Xiao B., et al. (1998) Neuron. 21:707-716; ; Mayya V., et al. (2009) Sci. Signal. 2:RA46-RA46

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.15M NaCl, 1mM DTT

Scientific Category

Neuroscience

NCBI Accession Number

NP_001139194

Uniprot Accession Number

Q9NSC5

Species

Human

AA Sequence

MSTAR EQPIFSTRAH VFQIDPATKR NWIPAGKHAL TVSYFYDATR NVYRIISIGG AKAIINSTVT PNMTFTKTSQ KFGQWADSRA NTVYGLGFAS EQHLTQFAEK FQEVKEAARL AREKSQDGGE LTSPALGLAS HQVPPSPLVS ANGPGEEKLF RSQSADAPGP TERERLKKML SEGSVGEVQW EAEFFALQDS NNKLAGALRE ANAAAAQWRQ QLEAQRAEAE RLRQRVAELE AQAASEVTPT GEKEGLGQGQ SLEQLEALVQ TKDQEIQTLK SQTGGPREAL EAAEREETQQ KVQDLETRNA ELEHQLRAME RSLEEARAER ERARAEVGRA AQLLDVSLFE LSELREGLAR LAEAAP