Recombinant human TXNL4A protein
Thioredoxin-like 4A, also known as TXNL4A, belongs to the Dim protein family. TXNL4A is a 142 amino acid protein that plays an essential role in pre-mRNA splicing. Due to a failure to express early zygotic transcripts, deletion of the gene encoding TXNL4A in Schizosaccharomyces pombe leads to embryonal lethality during gastrulation. Localized to the nucleus, TXNL4A interacts with hnRNP F, hnRNP H2, Cas-L and PQBP-1 to effect gene expression. Recombinant human TXNL4A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Thioredoxin-like 4A, DIB1, DIM1, HsT161, TXNL4, u5-15kD
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
19.3 kDa (166aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Zhang Y Z., et al. (1999) Physiol Genomics. 1:109-118.; ; Zhang Y Z., et al. (2000) Gene. 257: 33-43.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_006692
Uniprot Accession Number
P83876
Species
Human
AA Sequence
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Finegel SDS-PAGE Running Gel Solution (8%) + 500ml Finegel Buffer
HCG beta (CGB7) (NM_033142) Human Over-expression Lysate