Recombinant human Sulfotransferase 1B1/SULT1B1 protein

Sulfotransferase family, cytosolic, 1B, member 1, also known as SuLT1B1, is an enzyme that in humans is encoded by the SuLT1B1 gene. SuLT1B1 contains a binding site for the sulfate donor, 3-prime-phosphoadenosine 5-prime-phosphosulfate, and a cysteine residue conserved in the ST1 gene family of sulfotransferases. Sulfotransferases such as SuLT1B1 catalyze the biotransformation of a large number of endogenous compounds such as neurotransmitters, steroids, bile acids, and thyroid hormones, as well as drugs and xenobiotics. Recombinant human SuLT1B1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Sulfotransferase family cytosolic 1B member 1, Sulfotransferase family, cytosolic, 1B, member 1, ST1B1, ST1B2, SuLT1B2, Thyroid hormone sulfotransferase

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

37.4 kDa (320aa) confirmed by MALDI-TOF

Additionnal Information

SULT1B1, Sulfotransferase family cytosolic 1B member 1, Sulfotransferase family, cytosolic, 1B, member 1, ST1B1, ST1B2, SuLT1B2, ATGP1537-10 µg, ATGP1537-20 µg, ATGP1537-50 µg, ATGP1537-100 µg, ATGP1537-250 µg, ATGP1537-500 µg, ATGP1537-1 mg, ATGP1537-10, ATGP1537-20, ATGP1537-50, ATGP1537-100, ATGP1537-250, ATGP1537-500, ATGP1537-1

References & Citations

Meinl W., et al. (2001) Biochem Biophys Res Commun. 288 (4) :855-62.; ; Glatt H., et al. (2000) Toxicol Lett. 113: 341-8.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_055280

Uniprot Accession Number

O43704

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMLSPKD ILRKDLKLVH GYPMTCAFAS NWEKIEQFHS RPDDIVIATY PKSGTTWVSE IIDMILNDGD IEKCKRGFIT EKVPMLEMTL PGLRTSGIEQ LEKNPSPRIV KTHLPTDLLP KSFWENNCKM IYLARNAKDV SVSYYHFDLM NNLQPFPGTW EEYLEKFLTG KVAYGSWFTH VKNWWKKKEE HPILFLYYED MKENPKEEIK KIIRFLEKNL NDEILDRIIH HTSFEVMKDN PLVNYTHLPT TVMDHSKSPF MRKGTAGDWK NYFTVAQNEK FDAIYETEMS KTALQFRTEI