Recombinant human Syntaxin 12 protein

Syntaxin 12, also known as, belongs to the syntaxin family. Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. STX12 regulates protein transport between late endosomes and the trans-Golgi network and interacts with ABC1 (ATP-binding cassette transporter A1), a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I (apolipoprotein A-I) . Recombinant human STX12 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Syntaxin 12, STX13, STX14

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

31.0 kDa (272aa) confirmed by MALDI-TOF

Additionnal Information

Syntaxin12, Syntaxin 12, STX13, STX14, ATGP1536-10 µg, ATGP1536-20 µg, ATGP1536-50 µg, ATGP1536-100 µg, ATGP1536-250 µg, ATGP1536-500 µg, ATGP1536-1 mg, ATGP1536-10, ATGP1536-20, ATGP1536-50, ATGP1536-100, ATGP1536-250, ATGP1536-500, ATGP1536-1

References & Citations

Tang B L., et al. (1998) J Biol Chem. 273:6944-6950.; ; Prekeris R., et al. (1998) J Cell Biol. 143: 957-971.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol,1mM DTT

Scientific Category

Transportation

NCBI Accession Number

NP_803173.1

Uniprot Accession Number

Q86Y82

Species

Human

AA Sequence

MSYGPL DMYRNPGPSG PQLRDFSSII QTCSGNIQRI SQATAQIKNL MSQLGTKQDS SKLQENLQQL QHSTNQLAKE TNELLKELGS LPLPLSTSEQ RQQRLQKERL MNDFSAALNN FQAVQRRVSE KEKESIARAR AGSRLSAEER QREEQLVSFD SHEEWNQMQS QEDEVAITEQ DLELIKERET AIRQLEADIL DVNQIFKDLA MMIHDQGDLI DSIEANVESS EVHVERATEQ LQRAAYYQKK SR